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Pulications

2023

Songhao Zhang, Gaofeng Pei, Boya Li, Pilong Li*, Yi Lin*. Abnormal phase separation of biomacromolecules in human diseases. Acta Biochim Biophys Sin (Shanghai).  Jul 21;55(7):1133-1152.

https://doi.org/10.3724/abbs.2023139

 

Yanrong Zhuang#, Zhiyuan Li#, Shiyue Xiong#, Chujie Sun#, Boya Li, Shuangcheng Alivia Wu, Jiali Lyu, Xiang Shi, Liang Yang, Yutong Chen, Zhangbin Bao, Xi Li, Chuhanwen Sun, Yuling Chen, Haiteng Deng, Tingting Li, Qingfeng Wu, Ling Qi, Yue Huang, Xuerui Yang*Yi Lin*. Circadian clocks are modulated by compartmentalized oscillating translation. (2023) Cell. Jul 22;

https://doi.org/10.1016/j.cell.2023.05.045

Shuangcheng Alivia Wu, Chenchen Shen, Xiaoqiong Wei, Xiawei Zhang, Siwen Wang, Xinxin Chen, Mauricio Torres, You Lu, Liangguang Leo Lin, Huilun Helen Wang, Allen H. Hunter, Deyu Fang, Shengyi Sun, Magdalena I. Ivanova Yi Lin*, Ling Qi*. The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes (2023) Nature communication. May 30; 14(1):3132 

https://doi.org/10.1038/s41467-023-38690-4

Hongyao Sun#, Yutong Chen#, Kun Yan, Yanqiu Shao, Qiangfeng C Zhang, Yi Lin*, Qiaoran Xi*. Recruitment of TRIM33 to cell-context specific PML nuclear bodies regulates nodal signaling in mESCs. (2023) The Embo Journal. Feb 1; 42(3):e112058 

https://doi.org/10.15252/embj.2022112058

 

2022

Xiang Shi#, Yanrong Zhuang#, Zhenhua Chen#, Mingrui Xu, Junqi Kuang, Xue-Lian Sun, Lisen Gao, Xia Kuang, Huairen Zhang, Wei Li, Samuel Zheng Hao Wong, Chuanyu Liu, Longqi Liu, Danhua Jiang, Duanqing Pei, Yi Lin*, QingFeng Wu*. Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset. (2022) Science Advances. Nov 16; 8(46):eabq2987

https://doi.org/10.1126/sciadv.abq2987

 

Yifei Gao#, Xi Li#, Pilong Li*, Yi Lin*. A brief guideline for studies of phase-separated biomolecular condensates. (2022) Nature Chemical Biology. Nov 18; 18(12):1307-1318

https://doi.org/10.1038/s41589-022-01204-2

 

Yi Lin*, Xiaofeng Fang*, Phase separation in RNA biology. (2021)Journal of Genetics and Genomics. 48 (10) 872-880

https://doi.org/10.1016/j.jgg.2021.07.012

Previous

Yi Lin, Xiaoming Zhou, Masato Kato, Daifei Liu, Sina  Ghaemmaghami, Benjamin P. Tu, and Steven L. McKnight*, Redox-mediated regulation of an evolutionarily conserved cross-beta structure formed by the TDP43 LC domain. (2020) PNAS. 117(46) 28727-28734

 

https://doi.org/10.1073/pnas.2012216117

 

 

Dylan T. Murray#, Masato Kato#, Yi Lin, Kent R. Thurber, Ivan Hung, Steven L. McKnight*, and Robert Tycko*, Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of  Low-Complexity Domains. (2017) Cell. Oct 19; 171(3):615–627

 

https://doi.org/10.1016/j.cell.2017.08.048

 

 

Yi Lin#, Eiichiro Mori#, Masato Kato#, Siheng Xiang#, Leeju Wu, Ilmin Kwon* and Steven L. McKnight*, Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers. (2016) Cell. Oct 20; 167(3):789-802

 

https://doi.org/10.1016/j.cell.2016.10.003

 

 

Siheng Xiang, Masato Kato, Leeju C. Wu, Yi Lin, Ming Ding, Yajie Zhang, Yonghao Yu, Steven L. McKnight*, The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid- like Droplets, and Nuclei. (2015) Cell. Nov 5;163(4):829-39

 

https://doi.org/10.1016/j.cell.2015.10.040